We aim to understand the fundamental mechanisms as to how chromatin governs our ability to adapt to environmental stimuli in healthy tissues as well as during the onset/progression of metabolic disease. 

The Romero lab is focused on the transcriptional mechanisms of adaptation in skeletal muscle and its resident stem cells. Skeletal muscle Skeletal muscle makes up 40% of our entire body weight and ~30% of our energy expenditure at rest. Skeletal muscle also has the remarkable ability to regenerate after an injury due to its resident stem cells referred to as satellite cells. Our lab is particularly focused on understanding how environmental factors, such as diet and exercise, confers its positive benefits and how these signals are integrated into transcriptional responses.

Lab Techniques: Click the Image to learn more